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Urea cycle disorders

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My sister has been married to mky cousin. she have given birth to 4 children, the first 2 and the last were males and died of urea cycle disorder, suspected only from hyperammonemia in the 4th, and the 3rd is female and is living well. i want to be guided how to avoid the next children from suffering from UCD and also want to know where and how i may diagnose the exact enzyme or gene responsible for this disorder.

Rehmat shah
Mphil scholar (Pharmacology),
Deptt. of pharmacy,
University of peshawar
cell phone 00923459824130
Fax 0092919218131


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